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Podium Presentation: Fluid-Structure Interaction Simulation of Cardiac Leads in the Heart: Developing a Computational Model for use in Medical Device Design

Research Publication

Podium Presentation: Fluid-Structure Interaction Simulation of Cardiac Leads in the Heart: Developing a Computational Model for use in Medical Device Design. Hakizumwami Birali Runesha, Bogdan Florin Tanasoiu, Georgi Subashki, Arthur Erdman, Daniel Keefe. Design of Medical Devices Conference (2016)

Abstract

The cost to bring a medical device from concept to market, when exploring a large number of design parameters, continues to increase and often requires animal and clinical trials. Major advances in computational tools and visualization have paved the way to simulation-based design of a wide array of medical devices. As models for structural and fluid mechanics simulations improve, the next step is to couple fluid and structural simulations for a solution that can better capture the overall dynamics of a device. This talk reports on current progress and lessons learned by our interdisciplinary team, which is creating an "as accurate as possible" fluid-structure interaction (FSI) model for simulating the dynamics of the right atrium (RA) of a real heart, with and without an implanted pacemaker wire. This model-development project fits into a larger program of research on virtual prototyping of medical devices by coupling supercomputer-based simulation with interactive visual design tools and big data. This presentation will also present our ultimate goal which is to develop a computational model that fits appropriately into a simulation-based design workflow such that, with a robust computational model in hand, different parameters (e.g., lead wire geometry, mechanical properties) and scenarios (e.g., patient-specific anatomy) can be explored and visualized using innovative interactive design tools. Preliminary results will be presented.

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